Hepatitis B virus "escape" mutants.
نویسندگان
چکیده
منابع مشابه
Hepatitis B virus S gene escape mutants
Hepatitis B virus (HBV) can be classified into nine immunological subtypes or eight genotypes. The most prevalent genotypes in Asia are genotypes B and C. HBV is transmitted parenteraly and can produce either asymptomatic or symptomatic disease. Although the consequences of acute hepatitis B can be severe, serious sequelae are associated with chronic infections. HBV seroprevalence ranges from i...
متن کاملReported Series Resolution Took Hepatitis B Virus "escape" Mutants
days, and about 5-20% of patients still required laparotomy. 3 What is the prognosis after an ectopic pregnancy? Among 55 American women treated by salpingectomy or salpingostomy and followed up for three to 41 months 30 became pregnant again: 24 pregnancies were intrauterine and six were repeat ectopics.32 In a four to eight year follow up of 110 Finnish women (42 treated by conservative surge...
متن کاملPrevalence of Hepatitis B Virus, Genotypes, and Mutants in HBsAg-Positive Patients in Meerut, India
Background: Genetic changeability of hepatitis B virus (HBV) signifies a challenge for the sensitivity of immunologic and molecular diagnostics. Therefore, knowing the spread of HBV genotypes (GENs) and mutation has considerable impacts on treatment strategies, vaccination program, diagnosis, and prevention. The present study aimed to detect HBV GENs and mutants in HBsAg-positive patients. Meth...
متن کاملDrug-resistant and immune-escape hepatitis B virus mutants in HIV-infected hosts
HIV-HBV infected patients require optimal control of viral replication in order to prevent severe comorbidities, such as liver cirrhosis and hepatocellular carcinoma. The genetic diversity of HBV is a poorly investigated factor of such viral replication in HIV-infected hosts. HBV genome diversity can be differentiated in two major aspects: genotypic and phenotypic. Genotypic diversity is more r...
متن کاملHepatitis B virus: molecular virology and common mutants.
A high rate of viral turnover, combined with an error-prone polymerase, results in a very high frequency of mutational events during hepatitis B virus replication. Mutants may accumulate, particularly in individuals at advanced stages of persistent infection and with antibody- and cell-mediated immune responses to the virus. Specific mutants may be selected from these populations, especially by...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 1990
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.301.6760.1058